Started by Murphy's wife, Pamela Schein Murphy, in 2008, The R.E.S.T. Initiative, is a non-profit foundation that works to alleviate fear, anxiety and stress in cancer patients by bringing free therapeutic massage therapies directly into chemotherapy treatment rooms. Marc serves on the board of directors and contributes his time, food and restaurant space whenever possible.

Now serving New York City for more than 25 years, City Harvest is the world's first food rescue organization, dedicated to feeding the city's hungry men, women, and children. As a member of the City Harvest Food Council, Murphy gets together with other top chefs, restaurateurs, and others in the food industry to help fight hunger in the city.

Currently, the foodservice sector makes up the largest portion of the State’s tourism industry, employing more than 428,000 people and posting sales of more than $20 billion. Since 1935, the New York State Restaurant Association (NYSRA) has served as the voice of the foodservice industry and has grown to represent over 7,000 restaurants from Montauk to Buffalo. Marc is Vice President of the Manhattan Chapter and serves on the board of directors on the State Chapter.

The stageFARM is a non-profit off-broadway theater company dedicated to commissioning / producing relevant new plays for a new audience. The stageFARM is committed to producing plays by playwrights whose voices engage our restless generation. Marc serves on the board of directors.

Culintro, the Culinary Trade Organization for restaurant professionals unites all of those who work, represent, or are touched by the restaurant industry. Launched in 2008, Marc currently serves on the advisory board.